It's not very easy to transfer - because of both the competition for slots and the visa process. It depends on your firm as well - if they're actively looking to expand in the US, they'll be more accommodating than if they're a net exporter of people from the US. Given the economic climate, it's mainly just the big Indian outsourcing firms who currently have growth plans in the US.When you get there, life is pretty easy. Some firms and offices can be cut-throat, but no more so than in London, Paris, Toronto, Frankfurt, etc. For the most part, even in large multinationals, expect colleagues to have minimal understanding of your background or appreciation of prior experience outside the US.If you've been exposed to US media and culture, you'll find it easier to fit in, but as long as you're in a major metropolitan area there are lots of regional sub-cultures.